3-Methoxybenzenethiol → HCID 57799712, compound

HRID 2101049Notes

Reaction equation

HRID 2101049 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([SH:9])[CH:6]=[CH:7][CH:8]=1.Cl[C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[C:13]([NH:21][C:22]2[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=2)[N:12]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:9][C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[C:13]([NH:21][C:22]3[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=3)[N:12]=2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 849893-MethoxybenzenethiolHCID 57799635(1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

Product 1

HCID 57799712HCID 57799712, compound

Procedure

Similar procedure as described in example 305 was used, starting from 3-methoxy-benzenethiol and (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-(3-methoxy-phenylsulfanyl)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 363 (MH+).

Sources & evidence

ORD record
ord-f2e252a4e13e450cbfdabedec8674a67
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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