3-Methoxybenzenethiol → HCID 57799610, compound

HRID 2101050Notes

Reaction equation

HRID 2101050 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([SH:9])[CH:6]=[CH:7][CH:8]=1.Cl[C:11]1[C:20]2[C:15](=[CH:16][C:17]([O:21][CH3:22])=[CH:18][CH:19]=2)[CH:14]=[C:13]([NH:23][C:24]2[CH:28]=[C:27]([CH3:29])[NH:26][N:25]=2)[N:12]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:9][C:11]2[C:20]3[C:15](=[CH:16][C:17]([O:21][CH3:22])=[CH:18][CH:19]=3)[CH:14]=[C:13]([NH:23][C:24]3[CH:28]=[C:27]([CH3:29])[NH:26][N:25]=3)[N:12]=2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 849893-MethoxybenzenethiolHCID 57799674(1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

Product 1

HCID 57799610HCID 57799610, compound

Procedure

Similar procedure as described in example 305 was used, starting from 3-methoxy-benzenethiol and (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-(3-methoxy-phenylsulfanyl)-6-methoxy-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 393 (MH+).

Sources & evidence

ORD record
ord-dcd3a7ff3d9b4909bfafcc911522a6e6
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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