HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Fluorobenzenethiol → [1-(3-fluoro-phenylsulfanyl)-6-methoxy-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Fluorobenzenethiol | HCID 75710 | — |
| Reactant | (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799674 | — |
| Product | [1-(3-fluoro-phenylsulfanyl)-6-methoxy-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799542 | — |
Reaction Steps
Similar procedure as described in example 305 was used, starting from 3-fluoro-benzenethiol and (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-(3-fluoro-phenylsulfanyl)-6-methoxy-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 381 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-ab390e36599f459db2c78ede3fe4a905 |
| Source note | uspto-grants-2009_08 |