4,4,5,5-Tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolane → HCID 23633646, compound

HRID 2101093Notes

Reaction equation

HRID 2101093 reaction equation
Cl[C:2]1[N:3]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[CH:5]=[C:6]2[C:15]=1[CH:14]=[CH:13][C:12]1[O:11][CH2:10][CH2:9][O:8][C:7]2=1.[C:23](B1OC(C)(C)C(C)(C)O1)([CH3:25])=[CH2:24]>>[CH:23]([C:2]1[N:3]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[CH:5]=[C:6]2[C:15]=1[CH:14]=[CH:13][C:12]1[O:11][CH2:10][CH2:9][O:8][C:7]2=1)([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 109974264,4,5,5-Tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolaneHCID 57799784HCID 57799784, compound

Product 1

HCID 23633646HCID 23633646, compound

Procedure

Similar procedure as described in example 330 was used, starting from (8-Chloro-2,3-dihydro-1,4-dioxa-7-aza-phenanthren-6-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and isopropenylboronic acid pinacol ester to give (8-Isopropyl-2,3-dihydro-1,4-dioxa-7-aza-phenanthren-6-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 325(MH+).

Sources & evidence

ORD record
ord-f9a68b016ee84c98bfdf2ab41750d17f
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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