Malonic Acid → HCID 68857895, compound

HRID 2101095Notes

Reaction equation

HRID 2101095 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH2:11][CH2:12][O:13][CH3:14])[CH:5]=O.C(O)(=O)[CH2:16][C:17]([OH:19])=[O:18]>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:16][C:17]([OH:19])=[O:18])[CH:7]=[CH:8][C:9]=1[O:10][CH2:11][CH2:12][O:13][CH3:14]

Participants

3

Reactant 2

HCID 867Malonic AcidHCID 28603982HCID 28603982, compound

Product 1

HCID 68857895HCID 68857895, compound

Procedure

Similar procedure as described in example 343a was used, starting from 3-Fluoro-4-(2-methoxy-ethoxy)-benzaldehyde and malonic acid to give 3-[3-Fluoro-4-(2-methoxy-ethoxy)-phenyl]-acrylic acid. LC-MS: m/e 241 (MH+).

Sources & evidence

ORD record
ord-b2e79fa820724beb9a6c7c3ccc530fac
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

Loading…