4-Toluenesulfonyl chloride → HCID 57799559, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 8% 21 mL NaOH was added 5-Methoxy-4-methyl-indan-1,2-dione-2-oxime (2.2 g). The mixture was heated to 50° C. Then p-Toluenesulfonyl chloride (2.77 g) was added in portions to the mixture. The mixture was heated at 80° C. for another 15 min. After cooled to room temperature, the precipitate (a little) was removed from the mixture. Mother liquid was acidified by concentrated HCl to PH=3-4 and precipitate was formed. The precipitate was washed with water and dried for the next reaction.

Provenance & Evidence