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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101133Generated: October 30, 2026

Malonic Acid → 2-Chloro-3,4-dimethoxycinnamic acid

https://huagongshe.com/reaction/2101133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalonic AcidHCID 867—
Reactant2-ChloroveratraldehydeHCID 79445—
Product2-Chloro-3,4-dimethoxycinnamic acidHCID 2774967—

Reaction Steps

Similar procedure as described in example 9B was used, starting from 2-Chloro-3,4-dimethoxy-benzaldehyde and malonic acid to give 3-(2-Chloro-3,4-dimethoxy-phenyl)-acrylic acid. LC-MS: m/e 241 (M−1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-601b48534f694c8381bb2b6061940db0
Source noteuspto-grants-2009_08