N-Methylcyclohexylamine → HCID 57799792, compound

HRID 2101149Notes

Reaction equation

HRID 2101149 reaction equation
[CH:1]([O:4][C:5]1[C:14]2[C:9](=[CH:10][C:11]([C:15](O)=[O:16])=[CH:12][CH:13]=2)[CH:8]=[C:7]([NH:18][C:19]2[CH:23]=[C:22]([CH3:24])[NH:21][N:20]=2)[N:6]=1)([CH3:3])[CH3:2].[CH:25]1([NH:31][CH3:32])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[CH:25]1([N:31]([CH3:32])[C:15]([C:11]2[CH:10]=[C:9]3[C:14](=[CH:13][CH:12]=2)[C:5]([O:4][CH:1]([CH3:2])[CH3:3])=[N:6][C:7]([NH:18][C:19]2[CH:23]=[C:22]([CH3:24])[NH:21][N:20]=2)=[CH:8]3)=[O:16])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 7514N-MethylcyclohexylamineHCID 577994701-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-6-carboxylic acid

Product 1

HCID 57799792HCID 57799792, compound

Procedure

Similar procedure as described in example 384 was used, starting from 1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-6-carboxylic acid and Cyclohexyl-methyl-amine to give 1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-6-carboxylic acid cyclohexyl-methyl-amide. LC-MS: m/e 422 (MH+).

Sources & evidence

ORD record
ord-06f065793f4f4dc99d3591b2cccc26d2
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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