HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine, m-trifluoromethyl- → [4-(Isopropyl-dimethyl-silanyl)-benzyl]-[2-(3-trifluoromethyl-phenyl)-ethyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine, m-trifluoromethyl- | HCID 104223 | — |
| Reactant | 4-(Isopropyldimethylsilyl)benzaldehyde | HCID 57438509 | — |
| Product | [4-(Isopropyl-dimethyl-silanyl)-benzyl]-[2-(3-trifluoromethyl-phenyl)-ethyl]-amine | HCID 57438508 | — |
Reaction Steps
[4-(Isopropyl-dimethyl-silanyl)-benzyl]-[2-(3-trifluoromethyl-phenyl)-ethyl]-amine was prepared in analogy to example 1 from 4-(isopropyl-dimethyl-silanyl)-benzaldehyde and 2-(3-trifluoromethyl-phenyl)-ethylamine. MS (ISP): 380.2 (100) (M+H)+. 1HNMR (CDCl3, 300 MHz): δ 7.52-7.42 (m, 6H), 7.26 (d, J=7.8 Hz, 2H), 3.81 (s, 2H), 2.88-2.96 (m, 4H), 0.95 (m, 7H), 0.23 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572823B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-56efe17c1343428c861ee64cdc79e7f1 |
| Source note | uspto-grants-2009_08 |