3-Bromo-6-chloro-4-(4-chlorophenyl)-2-methylpyridine → 3-Bromo-4-(4-chlorophenyl)-6-hydrazinyl-2-methylpyridine

HRID 2101387Notes

Reaction equation

HRID 2101387 reaction equation
[Br:1][C:2]1[C:3]([CH3:16])=[N:4][C:5](Cl)=[CH:6][C:7]=1[C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=1.BrC1C([NH:32][NH2:33])=NC(C)=CC=1C1C=CC(Cl)=CC=1>>[Br:1][C:2]1[C:3]([CH3:16])=[N:4][C:5]([NH:32][NH2:33])=[CH:6][C:7]=1[C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 577994403-Bromo-6-chloro-4-(4-chlorophenyl)-2-methylpyridineHCID 577994593-Bromo-4-(4-chlorophenyl)-2-hydrazinyl-6-methylpyridine

Product 1

HCID 577994103-Bromo-4-(4-chlorophenyl)-6-hydrazinyl-2-methylpyridineYield 92%

Procedure

The title compound (200 mg, 92% yield) as a white solid was prepared from 3-bromo-6-chloro-4-(4-chlorophenyl)-2-methylpyridine (220 mg, 0.7 mmol) by procedures analogous to those used for the preparation of 3-bromo-4-(4-chlorophenyl)-2-hydrazinyl-6-methylpyridine. HPLC/MS: retention time=2.87 min, [M+H]+=312.2.

Sources & evidence

ORD record
ord-ada9c69d8eca4637aab9453022935e57
Source dataset
uspto-grants-2009_08
Patent number
US07572808B2

Reaction notes

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