HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 4-[(3-Aminopropyl)sulfanyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 57801265 | HCID 57801265 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-[(3-Aminopropyl)sulfanyl]phenol | HCID 15222061 | 68.4% |
Reaction Steps
2-[3-(4-Hydroxy-phenylsulfanyl)-propyl]-isoindole-1,3-dione (10.5 g) was dissolved in ethanol (450 ml) and treated with hydrazine monohydrate (17 ml) at 100° C. for 2 h in argon gas. Filtration and evaporation then crystallization from ethanol gave 4-(3-amino-propylsulfanyl)-phenol (4.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572908B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-bddf30004b704388a6bf3be6026007ea |
| Source note | uspto-grants-2009_08 |