HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoroisatin → 5-fluoro-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoroisatin | HCID 236566 | — |
| Solvent | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Product | 5-fluoro-1,3-dihydro-2H-indol-2-one | HCID 3731012 | — |
Reaction Steps
5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572924B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-506a0ed099c04336b88aeeddeec6dfdd |
| Source note | uspto-grants-2009_08 |