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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101604Generated: October 30, 2026

6-Phenyl-1,3-dihydro-indol-2-one → 2,4-Dimethyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amide

https://huagongshe.com/reaction/2101604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Phenyl-1,3-dihydro-indol-2-oneHCID 10536384—
Reactant5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-diethylamino-propyl)-amideHCID 20761799—
Product2,4-Dimethyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amideHCID 67280904—

Reaction Steps

6-Phenyl-1,3-dihydroindol-2-one (1.5 g, 7.16 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amide (2 g) to give 1.9 g (57%) of, the title compound as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572924B2
Source datasetuspto-grants-2009_08
ORD IDord-4e5352d8b2d44c9ea746181d56f5ec1d
Source noteuspto-grants-2009_08