2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide → HCID 67281654, compound

HRID 2101628Notes

Reaction equation

HRID 2101628 reaction equation
[CH3:1][N:2]([CH3:16])[S:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10](=[O:15])[CH2:9]2)(=[O:5])=[O:4].[CH2:17]([N:19]([CH2:34][CH3:35])[CH2:20][CH2:21][NH:22][C:23]([C:25]1[C:29]([CH3:30])=[C:28]([CH:31]=O)[NH:27][C:26]=1[CH3:33])=[O:24])[CH3:18]>>[CH2:34]([N:19]([CH2:17][CH3:18])[CH2:20][CH2:21][NH:22][C:23]([C:25]1[C:29]([CH3:30])=[C:28]([CH:31]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[C:6]([S:3](=[O:5])(=[O:4])[N:2]([CH3:16])[CH3:1])[CH:7]=3)[NH:11][C:10]2=[O:15])[NH:27][C:26]=1[CH3:33])=[O:24])[CH3:35]

Participants

3

Reactant 2

HCID 98161852-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamideHCID 20761785N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide

Product 1

HCID 67281654HCID 67281654, compoundYield 43.5%

Procedure

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide (90 mg, 0.38 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide (100 mg) to give 80 mg (43%) of the title compound as a yellow solid.

Sources & evidence

ORD record
ord-3d290e1a07354707a2d22cd930c1b649
Source dataset
uspto-grants-2009_08
Patent number
US07572924B2

Reaction notes

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