Aniline → 1H-Imidazole-2-carboxamide, 1-methyl-N,4,5-triphenyl-

HRID 2101688Notes

Reaction equation

HRID 2101688 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1([C:14]2[N:15]=[C:16]([C:26](O)=[O:27])[N:17]([CH3:25])[C:18]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:2]1([NH:1][C:26]([C:16]2[N:17]([CH3:25])[C:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[N:15]=2)=[O:27])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 22066062HCID 22066062, compound

Product 1

HCID 99465751H-Imidazole-2-carboxamide, 1-methyl-N,4,5-triphenyl-

Procedure

Using essentially the same procedure as Example 4, Step B, but using aniline (0.025 mL), 4,5-diphenyl-1-methylimidazole-2-carboxylic acid (30 mg, 0.10 mmol) from Example 4, Step A was converted to the title compound.

Sources & evidence

ORD record
ord-78230caff82145a9b176c6a0b562001d
Source dataset
uspto-grants-2009_08
Patent number
US07572785B2

Reaction notes

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