Hexyl isocyanate → N-(Hexyl)-4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-1-methylimidazole-2-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	Hexyl isocyanate	HCID 75659	—
Reactant	4-(4-Chlorophenyl)-5-(2,4-dichlorophenyl)-1-methylimidazole	HCID 22066083	—
Product	N-(Hexyl)-4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-1-methylimidazole-2-carboxamide	HCID 10226761	—

Reaction Steps

Using essentially the same procedure as Example 33, but using n-hexyl isocyanate (0.040 mL, 0.30 mmol), 4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-1-methylimidazole (50 mg, 0.15 mmol) from Example 32, Step C was converted to the title compound after purification twice by Prep TLC (25% ethyl acetate in hexanes).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07572785B2
Source dataset	uspto-grants-2009_08
ORD ID	ord-73ed897234124131b27998ecbd306353
Source note	uspto-grants-2009_08