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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 210181Generated: October 25, 2026

Dichloromethane → methyl 3-[4-[[3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]phenyl]propanoate

https://huagongshe.com/reaction/210181

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiphenylphosphinic chlorideHCID 73910—
ReactantDiisopropylethylamineHCID 81531—
ReactantMethyl 3-(4-aminophenyl)propanoateHCID 417374—
Reactant3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acidHCID 66688251—
Productmethyl 3-[4-[[3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]phenyl]propanoateHCID 178499924—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-04dba65e19174b71bcd608bf060e5847
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)