Picolyl chloride hydrochloride → HCID 24985970, compound

HRID 2101855Notes

Reaction equation

HRID 2101855 reaction equation
[Cl:1][C:2]1[C:10]([C:11]#[N:12])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[C:5]([CH:13]([F:15])[F:14])[NH:6]2.Cl.Cl[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][N:20]=1>>[Cl:1][C:2]1[C:10]([C:11]#[N:12])=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[C:5]([CH:13]([F:14])[F:15])[N:6]2[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][N:20]=1

Participants

3

Reactant 2

HCID 23392Picolyl chloride hydrochlorideHCID 249856324-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 24985970HCID 24985970, compound

Procedure

Synthesized as described in Example 39 from 4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile and 2-(chloromethyl)pyridine hydrochloride. MS (ESI) m/z 318.07 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-08d55a78b9334dcba0fb2c7164cb0859
Source dataset
uspto-grants-2009_08
Patent number
US07572820B2

Reaction notes

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