2-Chloro-3-(trifluoromethyl)benzoic acid → HCID 24984147, compound

HRID 2101885Notes

Reaction equation

HRID 2101885 reaction equation
[C:1]([C:3]1[C:4]([C:17]([F:20])([F:19])[F:18])=[C:5]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:12][C:13](=[NH:16])[NH:14][OH:15])[CH:7]=[CH:6]2)#[N:2].[Cl:21][C:22]1[C:30]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:28]=[CH:27][C:23]=1[C:24](O)=O>>[Cl:21][C:22]1[C:30]([C:31]([F:32])([F:33])[F:34])=[CH:29][CH:28]=[CH:27][C:23]=1[C:24]1[O:15][N:14]=[C:13]([CH2:12][N:8]2[C:9]3[C:5](=[C:4]([C:17]([F:19])([F:20])[F:18])[C:3]([C:1]#[N:2])=[CH:11][CH:10]=3)[CH:6]=[CH:7]2)[N:16]=1

Participants

3

Reactant 2

HCID 27366772-Chloro-3-(trifluoromethyl)benzoic acidHCID 178509476HCID 178509476, compound

Product 1

HCID 24984147HCID 24984147, compound

Procedure

Synthesized as described in Example 72 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 2-chloro-3-(trifluoromethyl)benzoic acid: MS (APCl): m/z 471 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-a25bc72673554e169b014df85c0948bf
Source dataset
uspto-grants-2009_08
Patent number
US07572820B2

Reaction notes

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