HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-4-chlorobenzoic acid → 1-{[5-(3-Bromo-4-chlorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-4-chlorobenzoic acid | HCID 2735544 | — |
| Reactant | HCID 178509476 | HCID 178509476 | — |
| Product | 1-{[5-(3-Bromo-4-chlorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67405454 | — |
Reaction Steps
Synthesized as described in Example 72 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 3-bromo-4-chlorobenzoic acid: MS (ESI): m/z 481 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572820B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-0a56c8a461c9402985cd001389071fcc |
| Source note | uspto-grants-2009_08 |