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3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole → 1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole | HCID 2797131 | — |
| 反応物 | 4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 67405449 | — |
| 生成物 | 1-({5-[4-(Methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 24984456 | — |
反応手順
Synthesized as described in Example 23 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[4-(methyloxy)phenyl]-1,2,4-oxadiazole: MS (ES) m/z 399 (M+1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07572820B2 |
| 出典データセット | uspto-grants-2009_08 |
| ORD ID | ord-21c355fcea2a4bc090de4e450d4188df |
| 出典メモ | uspto-grants-2009_08 |