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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101941Generated: October 30, 2026

4-(Chloromethyl)-1,3-thiazole → HCID 67404542, compound

https://huagongshe.com/reaction/2101941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-1,3-thiazoleHCID 2763290—
Reactant2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 53309346—
ProductHCID 67404542HCID 67404542—

Reaction Steps

Synthesized as described in Example 4 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile and 4-(chloromethyl)-1,3-thiazole: 1H NMR (400 MHz, CDCl3) δ 8.80 (d, J=2.0 Hz, 1H), 7.50 (m, 2H), 6.75 (s, 1H), 6.64 (s, 1H), 5.50 (s, 2H), 2.53 (s, 3H); MS (ES) m/z 322 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-649da2871c70490181a36bdfe5d26859
Source noteuspto-grants-2009_08