Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102011Generated: October 27, 2026

Trifluoroacetic acid → 5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole

https://huagongshe.com/reaction/2102011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-Bromo-3-chlorobenzene-1,2-diamineHCID 57800154—
Product5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazoleHCID 57800354—

Reaction Steps

Synthesized as described in Example 195C from 4-bromo-3-chloro-1,2-benzenediamine and TFA: MS (ESI) m/z 301 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-2f0f18d81fd74b80aa8cf088e70f3f7a
Source noteuspto-grants-2009_08