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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102012Generated: October 27, 2026

5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole → 4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile

https://huagongshe.com/reaction/2102012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazoleHCID 57800354—
ReactantHCID 178418546HCID 178418546—
Product4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrileHCID 67404532—

Reaction Steps

Synthesized as described in Example 197A from 5-bromo-4-chloro-2-(trifluoromethyl)-1H-benzimidazole and CuCN: MS (APCl) m/z 246 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-9ea23a8ee0f84d02b3410f5f03763f08
Source noteuspto-grants-2009_08