Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102032Generated: October 31, 2026

3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → 4-Chloro-2-methyl-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/2102032

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 2736622—
Reactant4-chloro-2-methyl-1H-indole-5-carbonitrileHCID 67404878—
Product4-Chloro-2-methyl-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrileHCID 57800316—

Reaction Steps

Synthesized as described in Example 4 from 4-chloro-2-methyl-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-b9e5825e6bc341f894e7d7eb22455fa9
Source noteuspto-grants-2009_08