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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102041Generated: October 30, 2026

3-(Chloromethyl)-5-(3,5-dimethylisoxazol-4-yl)-1,2,4-oxadiazole → 4-Chloro-1-{[5-(3,5-dimethyl-4-isoxazolyl)-1,2,4-oxadiazol-3-yl]methyl}-2-methyl-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/2102041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-(3,5-dimethylisoxazol-4-yl)-1,2,4-oxadiazoleHCID 2735760—
Reactant4-chloro-2-methyl-1H-indole-5-carbonitrileHCID 67404878—
Product4-Chloro-1-{[5-(3,5-dimethyl-4-isoxazolyl)-1,2,4-oxadiazol-3-yl]methyl}-2-methyl-1H-indole-5-carbonitrileHCID 57800122—

Reaction Steps

Synthesized as described in Example 4 from 4-chloro-2-methyl-1H-indole-5-carbonitrile and 3-(chloromethyl)-5-(3,5-dimethyl-4-isoxazolyl)-1,2,4-oxadiazole:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-48fd103a94ab4bca8278d12d85e71547
Source noteuspto-grants-2009_08