HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-(trifluoromethoxy)benzoic acid → 1-[(5-{3-Chloro-4-[(trifluoromethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)methyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-(trifluoromethoxy)benzoic acid | HCID 2773845 | — |
| Reactant | HCID 178509476 | HCID 178509476 | — |
| Product | 1-[(5-{3-Chloro-4-[(trifluoromethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)methyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 57800353 | — |
Reaction Steps
Synthesized as described in Example 241 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 3-chloro-4-[(trifluoromethyl)oxy]benzoic acid: MS (APCl) m/z 488 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572820B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-845e254538dc438da00e49b518a484ca |
| Source note | uspto-grants-2009_08 |