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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 210210Generated: October 29, 2026

Tetrahydrofuran → 7-{2-[1-(1-Ethoxycarbonylmethyl-butyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/210210

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
Reactanttert-Butyl 7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylateHCID 58230650—
Reactant3-(5-Hydroxy-indol-1-yl)-hexanoic acid ethyl esterHCID 67426394—
Product7-{2-[1-(1-Ethoxycarbonylmethyl-butyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl esterHCID 66821512—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-eef353d890fd425ca5d7c782fd8cd8bd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)