3,5-Bis-trifluoromethylphenylboronic acid → 1-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3,5-Bis-trifluoromethylphenylboronic acid	HCID 156265	—
Edukt	1-[(2-Bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 67404358	—
Produkt	1-({2-[3,5-bis(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 86620698	—

Reaktionsschritte

Synthesized as described in Example 310D using 1-[(2-bromo-1,3-thiazol-4-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 311B) and [3,5-bis(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 534 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07572820B2
Quelldatensatz	uspto-grants-2009_08
ORD ID	ord-3420c92d689b4a7fb4f52bfc50efaa34
Quellennotiz	uspto-grants-2009_08