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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2102185생성일: 2026년 10월 25일

(3,5-Difluorophenyl)boronic acid → 2-Cyclopropyl-1-{[5-(3,5-difluorophenyl)-2-furanyl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/2102185

반응식

참여 물질

역할이름HCID투입량
반응물(3,5-Difluorophenyl)boronic acidHCID 2734338—
반응물1-[(5-Bromo-2-furanyl)methyl]-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404993—
생성물2-Cyclopropyl-1-{[5-(3,5-difluorophenyl)-2-furanyl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405041—

반응 단계

Synthesizes as described in Example 310D using (1-[(5-bromo-2-furanyl)methyl]-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 310C) and (3,5-difluorophenyl)boronic acid: MS (ES) m/z 443 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07572820B2
출처 데이터셋uspto-grants-2009_08
ORD IDord-ccfc02d98f0e4f6a83fb9711ad179309
출처 메모uspto-grants-2009_08