돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2102188생성일: 2026년 10월 26일

4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole → 1-{[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methyl}-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/2102188

반응식

참여 물질

역할이름HCID투입량
반응물4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazoleHCID 610297—
반응물2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67404472—
생성물1-{[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]methyl}-2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67403833—

반응 단계

Synthesized as described in Example 4 using 2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 165A) and 4-(chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole: MS (ES) m/z 458 (M+1) and 460 (M+1, isotope).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07572820B2
출처 데이터셋uspto-grants-2009_08
ORD IDord-5e2979cf3a014d01af04412e7d9d30c0
출처 메모uspto-grants-2009_08