HCID 57800477, compound → HCID 86620726, compound

HRID 2102204Notes

Reaction equation

HRID 2102204 reaction equation
[CH:1]1([C:4]2[NH:5][C:6]3[C:11]([CH:12]=2)=[C:10]([C:13]([F:16])([F:15])[F:14])[C:9]([C:17]#[N:18])=[CH:8][CH:7]=3)[CH2:3][CH2:2]1.Br[CH2:20][C:21]1[O:25][C:24]([C:26]2[CH:31]=[CH:30][CH:29]=[C:28]([C:32]([F:35])([F:34])[F:33])[CH:27]=2)=[N:23][CH:22]=1>>[CH:1]1([C:4]2[N:5]([CH2:20][C:21]3[O:25][C:24]([C:26]4[CH:31]=[CH:30][CH:29]=[C:28]([C:32]([F:35])([F:33])[F:34])[CH:27]=4)=[N:23][CH:22]=3)[C:6]3[C:11]([CH:12]=2)=[C:10]([C:13]([F:14])([F:15])[F:16])[C:9]([C:17]#[N:18])=[CH:8][CH:7]=3)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 57800477HCID 57800477, compoundHCID 674044722-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 86620726HCID 86620726, compound

Procedure

Synthesized as described in Example 4 using 2-cyclopropyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 165A) and 5-(bromomethyl)-2-[3-(trifluoromethyl)phenyl]-1,3-oxazole (Example 370C): MS (ES) m/z 476 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-410f3fa80f5a41b6ac0dfab5eaa91dd2
Source dataset
uspto-grants-2009_08
Patent number
US07572820B2

Reaction notes

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