反应详情

温度

50 °C

3-Benzyloxy-5-bromo-4-[hydroxyl(4-methoxyphenyl)methyl]-1-isopropyl-1H-pyrazole (0.6 g) was dissolved in dichloromethane (10 mL). To the stirred solution was added Manganese dioxide (0.5 g) at room temperature and the mixture was stirred at 50° C. for 1 hour. After the insoluble material was removed by filtration, the filtrate was concentrated under reduced pressure to give the title compound (0.4 g).

1. customAfter the insoluble material was removed by filtration
2. concentrationthe filtrate was concentrated under reduced pressure