3-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one → 2-(Piperidin-4-yl)-1,2-dihydroisoquinolin-3(4H)-one

HRID 210236Notes

Reaction equation

HRID 210236 reaction equation
[NH:25]1[CH2:26][CH2:27][CH:28]([CH:29]2[CH2:30][c:31]3[c:32]([cH:33][cH:34][cH:35][cH:36]3)[NH:37][C:38]2=[O:39])[CH2:40][CH2:41]1.[O:1]=[C:2]1[N:3]([CH:12]2[CH2:13][CH2:14][N:15]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:16][CH2:17]2)[CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[CH2:11]1>>[O:1]=[C:2]1[N:3]([CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[CH2:11]1

Participants

3

Reactant 2

HCID 183212463-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-oneHCID 59731897tert-Butyl 4-(3-oxo-3,4-dihydroisoquinolin-2(1H)-yl)piperidine-1-carboxylate

Product 1

HCID 597318882-(Piperidin-4-yl)-1,2-dihydroisoquinolin-3(4H)-one

Sources & evidence

ORD record
ord-004e2632e85e4480a95016293d40d75a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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