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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102640Generated: October 30, 2026

Sodium Iodide → HCID 68908687, compound

https://huagongshe.com/reaction/2102640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantDimethylformamideHCID 6228—
ReactantPotassium CarbonateHCID 11430—
Reactant3-Butyl-8-azabicyclo[3,2,1]octaneHCID 68907966—
ProductHCID 68908687HCID 68908687—

Reaction Steps

Crude (R,S)-1-(3-chloro-2-methylpropyl)-3,4-dihydro-1H-quinolin-2-one (107LH63) (0.094 g), 3-butyl-8-azabicyclo[3.2.1]octane (0.025 g, 0.15 mmol), NaI (0.100 g, 0.67 mmol), and K2CO3 (0.075 g, 0.54 mmol) in DMF (1 mL) were reacted and purified according to GP20 to give the title compound (107LH74-c4) (0.025 g). HPLC-MS (ammonium acetate) [M+H]+=369.33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576078B2
Source datasetuspto-grants-2009_08
ORD IDord-19d1f5afba47428d984b5fa89ef22f20
Source noteuspto-grants-2009_08