Methyl 4-iodobenzoate → 4-(Cyclopropylethynyl)benzoic acid

HRID 2102889Notes

Reaction equation

HRID 2102889 reaction equation
[CH:1]1([C:4]#[C:5][C:6]2[CH:14]=[CH:13][C:9]([C:10]([OH:12])=[O:11])=[C:8](C)[CH:7]=2)[CH2:3][CH2:2]1.IC1C=CC(C(OC)=O)=CC=1>>[CH:1]1([C:4]#[C:5][C:6]2[CH:7]=[CH:8][C:9]([C:10]([OH:12])=[O:11])=[CH:13][CH:14]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 69273Methyl 4-iodobenzoateHCID 57804096HCID 57804096, compound

Product 1

HCID 445413724-(Cyclopropylethynyl)benzoic acid

Procedure

The above compound was prepared using the same procedure as 4-(cyclopropylethynyl)-2-methylbenzoic acid, except methyl 4-iodobenzoate was used as the starting material.

Workup

  1. customThe above compound was prepared

Sources & evidence

ORD record
ord-494e9dc244c348d99fda7255388aea5c
Source dataset
uspto-grants-2009_08
Patent number
US07576099B2

Reaction notes

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