HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178507362, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Lithium aluminum hydride | HCID 28112 | — |
| Reactant | 5-nitro-1H-indazole-3-carboxylic Acid | HCID 7144652 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178507362 | HCID 178507362 | 19.9% |
Reaction Steps
5-nitro-1H-indazole-3-carboxylic acid (500 mg, 0.002 mol) was dissolved in 50 mL THF, added lithium tetrahydroaluminate (366 mg, 0.00964 mol) portionwise and stirred at room temperature overnight. 65 mg (15%). Water (366 μL), 15% NaOH solution (366 μL), and water (1.1 mL) were added cautiously and the mixtured was filtered. The filtrate was concentrated under vacuum to give the product (65 mg, 15%) as an oil. m/z=160.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576099B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-a40430eef0f64edfacf221c4acfceaea |
| Source note | uspto-grants-2009_08 |