HCID 69055225, compound → HCID 11579635, compound

Participants

Reaction Steps

To a stirred solution of 4-methoxy-3,5,7,8-tetramethyl-3,4-dihydrospiro[chromene-2,1′-cyclobutan]-6-ol. (50 mg) in 10 mL of MeOH was added 5 drops of conc. HCl. The reaction mixture was concentrated, and the residue was purified by flash chromatography eluted with 40% ethyl acetate in hexane to give 7.6 mg of the desired product 3,5,7,8-tetramethyl-3,4-dihydrospiro[chromene-2,1′-cyclobutane]-4,6-diol as a white solid.

Provenance & Evidence