1-Chloro-4-(trifluoromethyl)benzene → HCID 22475186, compound

HRID 2103105Notes

Reaction equation

HRID 2103105 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](F)(F)F)=[CH:4][CH:3]=1.[Al+3].[Cl-:13].[Cl-:14].[Cl-].[F:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:20]2[CH:21]=[CH:22][C:17]([F:16])=[CH:18][CH:19]=2)([Cl:14])[Cl:13])=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 73941-Chloro-4-(trifluoromethyl)benzeneHCID 10008FluorobenzeneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 22475186HCID 22475186, compound

Procedure

From 4-chlorobenzotrifluoride (180 mg, 1 mmol), AlCl3 (400 mg, 3 mmol) and fluorobenzene (96 mg, 1 mmol), light yellow oil (382 mg, 131% crude).

Sources & evidence

ORD record
ord-3fe8bf603bf747dd8b0d0fd12757c0fb
Source dataset
uspto-grants-2009_08
Patent number
US07576088B2

Reaction notes

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