Ammonia → 2-(5-Benzenesulfonyl-indan-1-yloxy)-acetamide

HRID 2103345Notes

Reaction equation

HRID 2103345 reaction equation
C(O[C:4](=[O:26])[CH2:5][O:6][CH:7]1[C:16]2[C:11](=[CH:12][C:13]([S:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)(=[O:19])=[O:18])=[CH:14][CH:15]=2)C[CH2:9][CH2:8]1)C.[NH3:27]>>[C:20]1([S:17]([C:13]2[CH:14]=[C:15]3[C:16](=[CH:11][CH:12]=2)[CH:7]([O:6][CH2:5][C:4]([NH2:27])=[O:26])[CH2:8][CH2:9]3)(=[O:18])=[O:19])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 57804256(6-Benzenesulfonyl-1,2,3,4-tetrahydro-naphthalen-1-yloxy)-acetic acid ethyl ester

Product 1

HCID 578042512-(5-Benzenesulfonyl-indan-1-yloxy)-acetamide

Procedure

2-(5-Benzenesulfonyl-indan-1-yloxy)-acetamide was prepared from (6-benzenesulfonyl-1,2,3,4-tetrahydro-naphthalen-1-yloxy)-acetic acid ethyl ester using the procedure of step 3 of Example 1, but replacing the methylamine hydrochloride with ammonia. MS: 332 (M+H)+.

Sources & evidence

ORD record
ord-fdf732c5d28a4b65beb6fad74c2cf2ea
Source dataset
uspto-grants-2009_08
Patent number
US07576103B2

Reaction notes

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