HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-Benzenesulfonyl-1-chloro-1,2,3,4-tetrahydro-naphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Benzenesulfonyl-1,2,3,4-tetrahydro-naphthalen-1-ol | HCID 57526779 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-Benzenesulfonyl-1-chloro-1,2,3,4-tetrahydro-naphthalene | HCID 57526780 | 86.3% |
Reaction Steps
6-Benzenesulfonyl-1,2,3,4-tetrahydro-naphthalen-1-ol (0.65 g, 2.26 mmol) was dissolved in 50 mL toluene, and 1 mL of thionyl chloride was added. The reaction was refluxed for one hour, and then cooled. Solvent was removed under reduced pressure to yield 6-benzenesulfonyl-1-chloro-1,2,3,4-tetrahydro-naphthalene (0.6 g, 86.3%) as a crude oil. MS: 308 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576103B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-e490f96db39440e8b68838278df9d4f5 |
| Source note | uspto-grants-2009_08 |