HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 2-fluoro-4-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Fluoro-4-methylbenzoic acid | HCID 2736145 | — |
| Product | Methyl 2-fluoro-4-methylbenzoate | HCID 18759805 | — |
Reaction Steps
To a solution of 2-fluoro-4-methyl-benzoic acid (1.1 g, 7.13 mmol) in methanol (20 mL) add thionyl chloride (1.02 g, 8.56 mmol). Stir the resulting mixture overnight then concentrate under vacuum to give the title compound (1.2 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576109B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-da234380c63c44e486a19c0391a20831 |
| Source note | uspto-grants-2009_08 |