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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2103553Generated: October 25, 2026

3-[(5-Hydroxymethyl-furan-2-ylmethyl)-amino]-phthalic acid dimethyl ester → 3-[(5-Hydroxymethyl-furan-2-ylmethyl)-amino]-phthalic acid

https://huagongshe.com/reaction/2103553

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(5-Hydroxymethyl-furan-2-ylmethyl)-amino]-phthalic acid dimethyl esterHCID 21040137—
Reactant3-(2-Methoxy-ethylamino)-phthalic acidHCID 21988519—
Product3-[(5-Hydroxymethyl-furan-2-ylmethyl)-amino]-phthalic acidHCID 21988584—

Reaction Steps

3-[(5-Hydroxymethyl-furan-2-ylmethyl)-amino]-phthalic acid dimethyl ester (0.97 g, 3.04 mmol) was treated in the same manner as described above for the synthesis of 3-(2-methoxy-ethylamino)-phthalic acid. The product of the reaction, which contained a mixture of diacid and monomethyl esters, was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576104B2
Source datasetuspto-grants-2009_08
ORD IDord-65ddfbfc64f247d684b75a58b78805ab
Source noteuspto-grants-2009_08