Methanol → HCID 67084580, compound

HRID 2103591Notes

Reaction equation

HRID 2103591 reaction equation
[CH2:1]([O:3][C:4](=[O:19])/[C:5](/[C:11]1[CH:16]=[CH:15][C:14](SC)=[CH:13][CH:12]=1)=[CH:6]/[CH2:7][CH:8]([CH3:10])[CH3:9])[CH3:2].O[O:21][S:22]([O-:24])=O.[K+].[CH3:26]O>>[CH2:1]([O:3][C:4](=[O:19])/[C:5](/[C:11]1[CH:12]=[CH:13][C:14]([S:22]([CH3:26])(=[O:24])=[O:21])=[CH:15][CH:16]=1)=[CH:6]/[CH2:7][CH:8]([CH3:10])[CH3:9])[CH3:2]

Participants

4

Reactant 3

HCID 887MethanolHCID 23707502Potassium hydroxy sulfiteHCID 67084640HCID 67084640, compound

Product 1

HCID 67084580HCID 67084580, compound

Procedure

Following the method of example 54d, oxidation of (E)-5-methyl-2-(4-methylsulfanyl-phenyl)-hex-2-enoic acid ethyl ester (840 mg, 3.01 mmol) with oxone® (2.4 g, 3.9 mmol) in methanol gives the title compound as a yellow oil (848 mg). MS (m/e): 311 (M+H).

Sources & evidence

ORD record
ord-ac77786a52d1409a8991dded12aecb63
Source dataset
uspto-grants-2009_08
Patent number
US07576108B2

Reaction notes

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