Methanol → HCID 67084595, compound

HRID 2103592Notes

Reaction equation

HRID 2103592 reaction equation
[CH2:1]([O:3][C:4](=[O:20])[C:5]([C:12]1[CH:17]=[CH:16][C:15](SC)=[CH:14][CH:13]=1)=[CH:6][CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH3:2].O[O:22][S:23]([O-:25])=O.[K+].[CH3:27]O>>[CH2:1]([O:3][C:4](=[O:20])/[C:5](/[C:12]1[CH:13]=[CH:14][C:15]([S:23]([CH3:27])(=[O:25])=[O:22])=[CH:16][CH:17]=1)=[CH:6]/[CH2:7][CH2:8][CH:9]([CH3:10])[CH3:11])[CH3:2]

Participants

4

Reactant 3

HCID 887MethanolHCID 23707502Potassium hydroxy sulfiteHCID 67084565HCID 67084565, compound

Product 1

HCID 67084595HCID 67084595, compound

Procedure

Following the method of example 54d, oxidation of 6-methyl-2-(4-methylsulfanyl-phenyl)-hept-2-enoic acid ethyl ester (320 mg, 1.09 mmol) with oxone® (0.87 mg, 1.4 mmol) in methanol gives the title compound as a yellow oil (327 mg). MS (m/e): 325 (M+H).

Sources & evidence

ORD record
ord-ac8afd9746cf49b88e391b58c938c087
Source dataset
uspto-grants-2009_08
Patent number
US07576108B2

Reaction notes

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