HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → (E)-ethyl 3-cyclopentylacrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Cyclopentanecarbaldehyde | HCID 70106 | — |
| Reactant | HCID 178477249 | HCID 178477249 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (E)-ethyl 3-cyclopentylacrylate | HCID 11182849 | — |
Reaction Steps
Following the method of example 54a, reaction of triethylphosphinoacetate (196 g, 870 mmol) with hexane-washed sodium hydride (60% in mineral oil, 35 g, 870 mmol) in THF (1200 ml) and cyclopentanecarbaldehyde (86 g, 870 mmol) in THF (300 ml) gives the title product as an oil (59.1 g). MS (m/e): 169.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576108B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-0e2300ffdb7a4af29add24656ea50933 |
| Source note | uspto-grants-2009_08 |