HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → (Z)-2-bromo-3-cyclopentyl-acrylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | (E)-ethyl 3-cyclopentylacrylate | HCID 11182849 | — |
| Product | (Z)-2-bromo-3-cyclopentyl-acrylic acid ethyl ester | HCID 86605124 | 65% |
Reaction Steps
Following the method of example 54b, reaction of (E)-3-cyclopentyl-acrylic acid ethyl ester (87 g, 520 mmol) with bromine (29.3 ml, 572 mmol) and triethylamine (90 ml, 650 mmol) affords the title product as an oil (83.5 g) GC-MS (m/e): 247 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576108B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-478f92a3f8334cf5a8d37fdddb0a2542 |
| Source note | uspto-grants-2009_08 |