Diisobutylaluminum hydride → HCID 67486904, compound

Participants

Reaction Steps

According to method 16e was used (Z)-2-(4-bromo-cyclopenta-1,3-dienyl)-3-cyclohexyl-acrylic acid methyl ester (116.9 g, max. 0.338 mol), DIBALH (750 ml, 20% in toluene, 0.887 mol) to get 105 g crude product. Purify by silica gel chromatography, eluting with gradient 10:0 to 6:4 hexane:TBME to get 34.7 g pure compound. MS (m/e): 301.0/303.0 (M+H).

Provenance & Evidence