HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 3-(4-Bromo-phenylsulfanylmethyl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Bromothiophenol | HCID 66049 | — |
| Reactant | 3-(Bromomethyl)pyridine | HCID 245934 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-(4-Bromo-phenylsulfanylmethyl)-pyridine | HCID 13058739 | 85.9% |
Reaction Steps
Following method of example 9a, reaction of 4-bromo-benzenethiol (4.8 g, 24.1 mmol) with hydrobromic acid salt of 3-bromomethyl-pyridine (6.9 g, 26.5 mmol) and potassium carbonate (7.3 g, 53 mmol) in 91 ml acetone gives the title compound as a yellow solid (5.8 g). MS (m/e): 281 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576108B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-70303cb3f2fd4795b0afacdd68d096d4 |
| Source note | uspto-grants-2009_08 |