2-Methoxypyrimidine-5-boronic acid → HCID 178494070, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 1F, substituting the product of Example 52A for the product of Example 1E and substituting 2-methoxypyrimidine-5-boronic acid for pyrimidine-5-boronic acid. 1H NMR (500 MHz, CDCl3) δ ppm 8.77 (s, 2H) 8.07 (d, J=8.42 Hz, 1H) 7.98 (d, J=1.87 Hz, 1H) 7.60 (dd, J=8.42, 1.87 Hz, 2H) 4.09 (s, 3H) 3.76-3.89 (m, 1H) 3.51-3.66 (m, 1H) 2.95-3.05 (m, 1H) 2.53-2.74 (m, 4H) 2.14 (s, 3H) 1.03 (d, J=6.55 Hz, 6H). MS: (M+H)+=369.

Provenance & Evidence